Hu Rong

                Publisher:基礎醫學Release time:2017-12-26Times of browsing:219

                Rong Hu, Ph.D. Professor

                 Department of Physiology

                 School of Basic Medical Sciences and Clinical Pharmacy

                 China Pharmaceutical University

                 24 Tongjiaxiang

                 Nanjing, 210009

                 86(25) 83271029



                Rutgers, the State University of New Jersey, Piscataway, NJ

                Department of Pharmaceutics, Ernest Mario School of Pharmacy

                Ph. D. conferred June, 2005

                Major: Pharmaceutical Sciences

                RESEARCH INTEREST

                (1) Studies on phytochemicals-mediated cellular signaling and chemoprevention against inflammation-associated carcinogenesis. (2) Nrf2- and Nlrp3-mediated signaling in regulating oxidative stress and inflammation.


                1. Liu XZhang XDing YZhou WTao LLu PWang YHu R*. Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming. Antioxid Redox Signal. 2016 Aug 9. [Epub ahead of print]

                2. Liu XZhou WZhang XLu PDu QTao LDing YWang YHu R*. Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation. BiochemPharmacol. 2016 Jul 15;112:37-49. doi: 10.1016/j.bcp.2016.05.002. Epub 2016 May 13.

                3. Du QWang YLiu CWang HFan HLi YWang JZhang XLu JJi H*, Hu R*. Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis. Oncotarget. 2016 Feb 21. doi: 10.18632/oncotarget.7554.

                4.  Du Q, Wang Q, Fan H, Wang J, Liu X, Wang H, Wang Y*, Hu R*. Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome. Biochem Pharmacol. 2016 Feb 24. pii: S0006-2952(16)00116-7. doi: 10.1016/j.bcp.2016.02.017.

                5.  Wang Y, Wang H, Qian C, Tang J, Zhou W, Liu X, You Q*, Hu R*. 3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome. Biochem Pharmacol. 2016 Feb 1;101:71-86.