Fang Weirong

                Publisher:基礎醫學Release time:2017-12-26Times of browsing:242

                FANG, WEIRONG

                Associate Professor of Pharmacology

                School of Basic Medical Sciences and Clinical Pharmacy

                Phone: 86-25-83271173

                Email: weirongfang@cpu.edu.cn

                Research Summary

                My research mainly focus on cardiovascular pharmacology, especially on ischemic stroke which is one of the leading cause of death all over the world. Injury induced by stroke is not restricted in the brain only. Instead, brain interacts with peripheral organs, including the immune system. Circulating leukocytes impact on brain injury after stroke, and immune cells are also involved in the long term recovery after stroke. Leukocytes in the ischemic brain include macrophages, which are composed of microglia and monocyte-derived macrophages. How macrophages derived from monocytes and microglia contribute to brain injury remain unclear. Discovering function of immune cell will facilitate their clinical translation.

                Education

                2007-2011       Ph.D., Pharmacology, China Pharmaceutical University

                2001-2004       M.S., Pharmacology, China Pharmaceutical University

                1997-2001       B.S., Medicinal business management, China Pharmaceutical University.

                Academic Experience

                2012-      Associate Professor of Pharmacology, China Pharmaceutical University

                Awards and Honors

                2016       Academic leader of young and middle-aged teacher, Qing Lan Project, Jiangsu Provincial Department of Education

                2012       Outstanding young mainstay teacher, Qing Lan Project, Jiangsu Provincial Department of Education

                2013       “333” high level scientist project, third level, Jiangsu province

                Publications

                Books: Yunman li, Weirong Fang. Cardiovascular pharmacology. Jiangsu Science Press. 2014

                Papers and Articles (5 of 25)

                1. Fang W, Sha L, Kodithuwakku ND, Wei J, Zhang R, Han D, Mao L, Li Y. Attenuated Blood-Brain Barrier Dysfunction by XQ-1H Following Ischemic Stroke in Hyperlipidemic Rats. Mol Neurobiol. 2015; 52(1): 162-75. (SCI,IF: 5.397)

                2.  Han D, Fang W, Zhang R, Wei J, Kodithuwakku ND, Sha L, Ma W, Liu L, Li F, Li Y. Clematichinenoside protects blood brain barrier against ischemic stroke superimposed on systemic inflammatory challenges through up-regulating A20. Brain Behav Immun. 2016; 51: 56-69. (SCI,Co-first author,IF: 5.964)

                3. Fang W, Zhang R, Sha L, Lv P, Shang E, Han D, Wei J, Geng X, Yang Q, Li Y. Platelet activating factor induces transient blood-brain barrier opening to facilitate edaravone penetration into the brain. J Neurochem. 2014; 128(5): 662-71.(SCI,IF4.281)

                4.  Han D, Wei J, Zhang R, Ma W, Shen C, Feng Y, Xia N, Xu D, Cai D, Li Y, Fang W. Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemic animals through the suppression of TLR4 signaling. Sci Rep. 2016; 6:35319. doi: 10.1038/srep35319. (SCI,Co-corresponding author,IF4.259)

                5.  Huang J, Kodithuwakku ND, He W, Zhou Y, Fan W, Fang W, He G, Wu Q, Chu S, Li Y. The neuroprotective effect of a novel agent N2 on rat cerebral ischemia associated with the activation of PI3K/Akt signaling pathway. Neuropharmacology. 95 (2015): 12-21. (SCI,Co-corresponding author,IF4.936)


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